PLO20 Flowable™ represents the next generation of pluronic lecithin organogel (PLO) bases, it is a robust, ready-­to-­use transdermal base. This cosmetically elegant base has a lotion consistency that allows for incorporating high levels of APIs. It contains the same stability properties as PLO20 Non-Flowable™, allowing for versatile compounding. PLO20 Flowable™ provides enhanced chemical penetration that allows a deeper skin permeation than does PLO20 Non-Flowable™. This product is designed to accept the incorporation of high levels of lipophilic actives and moderate levels of hydrophilic actives.